Should you consider AIP in the differential diagnosis?1
The most common symptom of an acute attack associated with AIP is severe abdominal pain. However, 5-10% of patients may not experience the most common signs and symptoms of the disorder. Patients with Acute Intermittent Porphyria can also present with some or all of the following:
- Pain in the extremities, back, chest, neck, or head
- Mental symptoms
- Systemic arterial hypertension
- Respiratory paralysis
Index of suspicion1
Consider Acute Intermittent Porphyria in patients with unexplained recurring abdominal pain and other signs and symptoms of the disorder, particularly neuropsychiatric features. A number of precipitating factors are also believed to cause or exacerbate attacks, including some that are unknown. These may include:
- Various prescription medications
- Illicit drugs
- Alcohol use
- Crash dieting
- Endogenous hormones
Real Patients, Real Stories
Hearing about other peoples' experiences with the disease can help patients relate and better understand the disorder, so be sure to share these videos with your patients as well.
Learn how Lisa struggled with the painful and debilitating symptoms of AIP, and the journey she took to get diagnosed.
Watch this video to learn how Amy educated herself and worked with her doctors to arrive at a diagnosis of AIP.